CV
Division of Immunology, Boston Children’s Hospital, Karp Family Building, Boston, MA 02115, USA, +1 6174127513 marcoschdez37@gmail.com
Education
- 2017 - Sep 2021
National Autonomous University of Mexico (UNAM) Grade 9.4/10 Center for Genomic Sciences, Cuernavaca, México B.Sc. Genomics
Research Work Experience
- Nov 2021 - Present
Research Assistant at Boston Children’s Hospital, Harvard Medical School Boston, MA, USA. Advisor: Dr. Maria Gutierrez-Arcelus. Systems immunology: Analyzed bulk and single-cell RNA-seq data of immune cell types Identified relevant cell type for ankylosing spondylitis by integrating GWAS with transcriptomics Analyze TCR-sequencing data to identify expanded t-cell receptor gene in multisystemic inflammatory syndrome in children Created interactive web pages to visualize functional genomics datasets
- July 2021 – Sep 2021
Research Intern at Bellvitge Biomedical Research Institute (IDIBELL) Barcelona, Catalonia, Spain. Advisor: Dr. Álvaro Aytes. Transcriptomics of androgen receptor mutants PC3 cells
- Feb 2020 - Jun 2021
Research Intern at Sequencing and Bioinformatics Unit, Institute of Biotechnology, UNAM Cuernavaca, Morelos, Mexico. Advisor: Dr. Fidel Alejandro Sánchez Flores Transcriptome of LNCAP cells treated with AZD5363.
- Dec 2019 - Jan 2020
Research Intern at Instituto Aggeu Magalhães, FIOCRUZ Recife, Pernambuco, Brazil. Advisor: Dr. Antônio Mauro Rezende. Transcriptome of Aedes aegypti colony chronically exposed to the larvicide Bti
- Sep 2019 - Dec 2019
Research Intern at Department of Molecular Microbiology, Institute of Biotechnology, UNAM
Cuernavaca, Morelos, Mexico. Advisor: Dr. Sabino Pacheco Guillén
Projects related to Bacillus thuringiensis and insecticidal proteins
Guide RNA design and in vitro test for CRISPR-Cas9.
Phylogenetics of Bacillus thuringiensis GR007.
Learning molecular biology techniques: PCR, Gel electrophoresis, DNA extraction, Cloning of Cry genes, and protein purification.
Technical Skills
Bioinformatics
Programming: R, Bash, Python. Git/GitHub.
Bulk / single-cell RNA-seq: quality control, differential expression, pathway enrichment analysis.
Integration of transcriptomics with GWAS: colocalization analysis, identification of disease-relevant cell types score.
TCR-sequencing.
Genome assembly and annotation.
Data visualization, interactive and static web pages.
ADDITIONAL COURSES
Genomics
- Johns Hopkins University (JHU), Introduction to Genomic Technologies
- JHU Statistics for Genomic Data Science
- JHU Bioconductor for Genomic Data Science
- JHU Python for Genomic Data Science
- JHU Algorithms for DNA Sequencing
- JHU Understanding Prostate Cancer
- JHU Genomic Data Science with Galaxy
- JHU Command Line Tools for Genomic Data Science
- DTU, Whole genome sequencing of bacterial genomes - tools and application
Others
- UNAM, Management skills (5 courses and 1 capstone)
- Using Shiny to Plot Differential Gene Expression
- JHU Fundamentals of Immunology: Innate Immunity and B-Cell Function, Investment management: Meeting Investors’ Goals, Portfolio and Risk Management, Securing Investment Returns in the Long Run, Understanding Financial Markets.
GRANTS AND AWARDS
- Nov 2022 Joint Biology Consortium Microgrant ($5K) off parent award NIH/NIAMS 2P30 AR070253.
- Sep 2021 Honorific Mention B.Sc. in Genomic Sciences
- Summer 2021 National Autonomous University of Mexico Scholarship “Initiation to Research” to perform an internship at Barcelona, Spain Results:418073593
- 2017 Top Student in high school, GPA: 4.0